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Key role of T cell defects in age-related vulnerability to West Nile virus

West Nile virus (WNV) infection causes a life-threatening meningoencephalitis that becomes increasingly more prevalent over the age of 50 and is 40–50× more prevalent in people over the age of 70, compared with adults under the age of 40. In a mouse model of age-related vulnerability to WNV, we demo...

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Détails bibliographiques
Auteurs principaux: Brien, James D., Uhrlaub, Jennifer L., Hirsch, Alec, Wiley, Clayton A., Nikolich-Žugich, Janko
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2806630/
https://ncbi.nlm.nih.gov/pubmed/19901080
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20090222
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