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Increased apoptosis, curtailed expansion and incomplete differentiation of CD8(+) T-cells combine to decrease clearance of L. monocytogenes in old mice
Aging is accompanied by altered immunity, resulting in a variable state of poorly understood immunodeficiency. While both the numbers and the functionality of naïve T-cells are decreased by aging, the impact of these changes upon immune defense against bacterial pathogens in vivo remains understudie...
Tallennettuna:
| Päätekijät: | , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2011
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3517163/ https://ncbi.nlm.nih.gov/pubmed/21469120 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201041141 |
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