DNA Methylation of PTGIS Enhances Hepatic Stellate Cells Activation and Liver Fibrogenesis

The activation of hepatic stellate cells (HSCs) is a central event in the progression of liver fibrosis. Multiple studies proved that DNA methylation might accelerate HSCs activation. However, the specific pathogenesis of liver fibrosis remains not fully addressed. Our laboratory performed Genome me...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Pan, Xue-yin, Yang, Yang, Meng, Hong-wu, Li, Hai-di, Chen, Xin, Huang, Hui-min, Bu, Fang-tian, Yu, Hai-xia, Wang, Qin, Huang, Cheng, Meng, Xiao-ming, Li, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5985735/
https://ncbi.nlm.nih.gov/pubmed/29892223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00553
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