DNA Methylation of PTGIS Enhances Hepatic Stellate Cells Activation and Liver Fibrogenesis

The activation of hepatic stellate cells (HSCs) is a central event in the progression of liver fibrosis. Multiple studies proved that DNA methylation might accelerate HSCs activation. However, the specific pathogenesis of liver fibrosis remains not fully addressed. Our laboratory performed Genome me...

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Enregistré dans:
Détails bibliographiques
Publié dans:Front Pharmacol
Auteurs principaux: Pan, Xue-yin, Yang, Yang, Meng, Hong-wu, Li, Hai-di, Chen, Xin, Huang, Hui-min, Bu, Fang-tian, Yu, Hai-xia, Wang, Qin, Huang, Cheng, Meng, Xiao-ming, Li, Jun
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2018
Sujets:
Pharmacology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5985735/
https://ncbi.nlm.nih.gov/pubmed/29892223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00553
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