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Suppression of SUN2 by DNA methylation is associated with HSCs activation and hepatic fibrosis

Hepatic myofibroblasts, activated hepatic stellate cells (HSCs), are the main cell type of extracellular matrix (ECM) deposition during hepatic fibrosis. Aberrant DNA methylation-regulated HSCs activation in liver fibrogenesis has been reported, but the functional roles and mechanisms of DNA methyla...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Chen, Xin, Li, Wan-Xia, Chen, Yu, Li, Xiao-Feng, Li, Hai-Di, Huang, Hui-Min, Bu, Fang-Tian, Pan, Xue-Yin, Yang, Yang, Huang, Cheng, Meng, Xiao-Ming, Li, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6170444/
https://ncbi.nlm.nih.gov/pubmed/30282980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-1032-9
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