DNA Methylation of PTGIS Enhances Hepatic Stellate Cells Activation and Liver Fibrogenesis

The activation of hepatic stellate cells (HSCs) is a central event in the progression of liver fibrosis. Multiple studies proved that DNA methylation might accelerate HSCs activation. However, the specific pathogenesis of liver fibrosis remains not fully addressed. Our laboratory performed Genome me...

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Bibliografiska uppgifter
I publikationen:Front Pharmacol
Huvudupphovsmän: Pan, Xue-yin, Yang, Yang, Meng, Hong-wu, Li, Hai-di, Chen, Xin, Huang, Hui-min, Bu, Fang-tian, Yu, Hai-xia, Wang, Qin, Huang, Cheng, Meng, Xiao-ming, Li, Jun
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2018
Ämnen:
Pharmacology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5985735/
https://ncbi.nlm.nih.gov/pubmed/29892223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00553
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