DNA Methylation of PTGIS Enhances Hepatic Stellate Cells Activation and Liver Fibrogenesis

The activation of hepatic stellate cells (HSCs) is a central event in the progression of liver fibrosis. Multiple studies proved that DNA methylation might accelerate HSCs activation. However, the specific pathogenesis of liver fibrosis remains not fully addressed. Our laboratory performed Genome me...

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Bibliografske podrobnosti
izdano v:Front Pharmacol
Main Authors: Pan, Xue-yin, Yang, Yang, Meng, Hong-wu, Li, Hai-di, Chen, Xin, Huang, Hui-min, Bu, Fang-tian, Yu, Hai-xia, Wang, Qin, Huang, Cheng, Meng, Xiao-ming, Li, Jun
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2018
Teme:
Pharmacology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5985735/
https://ncbi.nlm.nih.gov/pubmed/29892223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00553
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