Caricamento...
Comprehensive Analysis of Constraint on the Spatial Distribution of Missense Variants in Human Protein Structures
The spatial distribution of genetic variation within proteins is shaped by evolutionary constraint and provides insight into the functional importance of protein regions and the potential pathogenicity of protein alterations. Here, we comprehensively evaluate the 3D spatial patterns of human germlin...
Salvato in:
| Pubblicato in: | Am J Hum Genet |
|---|---|
| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Elsevier
2018
|
| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5985282/ https://ncbi.nlm.nih.gov/pubmed/29455857 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2018.01.017 |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !
|