טוען...
Comprehensive Analysis of Constraint on the Spatial Distribution of Missense Variants in Human Protein Structures
The spatial distribution of genetic variation within proteins is shaped by evolutionary constraint and provides insight into the functional importance of protein regions and the potential pathogenicity of protein alterations. Here, we comprehensively evaluate the 3D spatial patterns of human germlin...
שמור ב:
| הוצא לאור ב: | Am J Hum Genet |
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| Main Authors: | , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Elsevier
2018
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5985282/ https://ncbi.nlm.nih.gov/pubmed/29455857 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2018.01.017 |
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