Φορτώνει......
Comprehensive Analysis of Constraint on the Spatial Distribution of Missense Variants in Human Protein Structures
The spatial distribution of genetic variation within proteins is shaped by evolutionary constraint and provides insight into the functional importance of protein regions and the potential pathogenicity of protein alterations. Here, we comprehensively evaluate the 3D spatial patterns of human germlin...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Am J Hum Genet |
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| Κύριοι συγγραφείς: | , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Elsevier
2018
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5985282/ https://ncbi.nlm.nih.gov/pubmed/29455857 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2018.01.017 |
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