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MMP Secretion Rate and Inter-invadopodia Spacing Collectively Govern Cancer Invasiveness
Invadopodia are micron-sized invasive structures that mediate extracellular matrix (ECM) degradation through a combination of membrane-bound and soluble matrix metalloproteinases (MMPs). However, how such localized degradation is converted into pores big enough for cancer cells to invade, and the re...
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| Publié dans: | Biophys J |
|---|---|
| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
The Biophysical Society
2018
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5985010/ https://ncbi.nlm.nih.gov/pubmed/29414711 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.11.3777 |
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