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MMP Secretion Rate and Inter-invadopodia Spacing Collectively Govern Cancer Invasiveness

Invadopodia are micron-sized invasive structures that mediate extracellular matrix (ECM) degradation through a combination of membrane-bound and soluble matrix metalloproteinases (MMPs). However, how such localized degradation is converted into pores big enough for cancer cells to invade, and the re...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Kumar, Sandeep, Das, Alakesh, Barai, Amlan, Sen, Shamik
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5985010/
https://ncbi.nlm.nih.gov/pubmed/29414711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.11.3777
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