Exosome secretion is enhanced by invadopodia and drives invasive behavior

Unconventional secretion of exosome vesicles from multivesicular endosomes (MVE) occurs across a broad set of systems and is reported to be upregulated in cancer where it promotes aggressive behavior. However, regulatory control of exosome secretion is poorly understood. Using cancer cells, we ident...

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Main Authors: Hoshino, Daisuke, Kirkbride, Kellye C., Costello, Kaitlin, Clark, Emily S., Sinha, Seema, Grega-Larson, Nathan, Tyska, Matthew J., Weaver, Alissa M.
Format: Artigo
Sprog:Inglês
Udgivet: 2013
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3873329/
https://ncbi.nlm.nih.gov/pubmed/24290760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.10.050
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