Cortactin promotes exosome secretion by controlling branched actin dynamics

Exosomes are extracellular vesicles that influence cellular behavior and enhance cancer aggressiveness by carrying bioactive molecules. The mechanisms that regulate exosome secretion are poorly understood. Here, we show that the actin cytoskeletal regulatory protein cortactin promotes exosome secret...

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Vydáno v:J Cell Biol
Hlavní autoři: Sinha, Seema, Hoshino, Daisuke, Hong, Nan Hyung, Kirkbride, Kellye C., Grega-Larson, Nathan E., Seiki, Motoharu, Tyska, Matthew J., Weaver, Alissa M.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2016
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4949450/
https://ncbi.nlm.nih.gov/pubmed/27402952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201601025
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