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MMP proteolytic activity regulates cancer invasiveness by modulating integrins

Cancer invasion through dense extracellular matrices (ECMs) is mediated by matrix metalloproteinases (MMPs) which degrade the ECM thereby creating paths for migration. However, how this degradation influences the phenotype of cancer cells is not fully clear. Here we address this question by probing...

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Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Das, Alakesh, Monteiro, Melissa, Barai, Amlan, Kumar, Sandeep, Sen, Shamik
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5660204/
https://ncbi.nlm.nih.gov/pubmed/29079818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-14340-w
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