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Lipid-Protein Interplay in Dimerization of Juxtamembrane Domains of Epidermal Growth Factor Receptor

Transmembrane (TM) helix and juxtamembrane (JM) domains (TM-JM) bridge the extracellular and intracellular domains of single-pass membrane proteins, including epidermal growth factor receptor (EGFR). TM-JM dimerization plays a crucial role in regulation of EGFR kinase activity at the cytoplasmic sid...

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Publicat a:Biophys J
Autors principals: Maeda, Ryo, Sato, Takeshi, Okamoto, Kenji, Yanagawa, Masataka, Sako, Yasushi
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5984969/
https://ncbi.nlm.nih.gov/pubmed/29490249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.12.029
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