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FGFR3 unliganded dimer stabilization by the juxtamembrane domain

Receptor Tyrosine Kinases (RTKs) conduct biochemical signals upon dimerization in the membrane plane. While RTKs are generally known to be activated in response to ligand binding, many of these receptors are capable of forming unliganded dimers that are likely important intermediates in the signalin...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Mol Biol
Hauptverfasser: Sarabipour, Sarvenaz, Hristova, Kalina
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4380549/
https://ncbi.nlm.nih.gov/pubmed/25688803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2015.02.013
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