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FGFR3 unliganded dimer stabilization by the juxtamembrane domain

Receptor Tyrosine Kinases (RTKs) conduct biochemical signals upon dimerization in the membrane plane. While RTKs are generally known to be activated in response to ligand binding, many of these receptors are capable of forming unliganded dimers that are likely important intermediates in the signalin...

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Vydáno v:J Mol Biol
Hlavní autoři: Sarabipour, Sarvenaz, Hristova, Kalina
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4380549/
https://ncbi.nlm.nih.gov/pubmed/25688803
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2015.02.013
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