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UMI-count modeling and differential expression analysis for single-cell RNA sequencing
Read counting and unique molecular identifier (UMI) counting are the principal gene expression quantification schemes used in single-cell RNA-sequencing (scRNA-seq) analysis. By using multiple scRNA-seq datasets, we reveal distinct distribution differences between these schemes and conclude that the...
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| Publicado no: | Genome Biol |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5984373/ https://ncbi.nlm.nih.gov/pubmed/29855333 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-018-1438-9 |
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