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Non-linear Normalization for Non-UMI Single Cell RNA-Seq
Single cell RNA-seq data, like data from other sequencing technology, contain systematic technical noise. Such noise results from a combined effect of unequal efficiencies in the capturing and counting of mRNA molecules, such as extraction/amplification efficiency and sequencing depth. We show that...
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| Udgivet i: | Front Genet |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Frontiers Media S.A.
2021
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8063035/ https://ncbi.nlm.nih.gov/pubmed/33897755 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2021.612670 |
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