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Normalization Methods on Single-Cell RNA-seq Data: An Empirical Survey
Data normalization is vital to single-cell sequencing, addressing limitations presented by low input material and various forms of bias or noise present in the sequencing process. Several such normalization methods exist, some of which rely on spike-in genes, molecules added in known quantities to s...
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| Udgivet i: | Front Genet |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Frontiers Media S.A.
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7019105/ https://ncbi.nlm.nih.gov/pubmed/32117453 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2020.00041 |
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