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SCnorm: robust normalization of single-cell RNA-seq data
Normalization of RNA-sequencing data is essential for accurate downstream inference, but the assumptions upon which most methods are based do not hold in the single-cell setting. Consequently, applying existing normalization methods to single-cell RNA-seq data introduces artifacts that bias downstre...
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| Publicado no: | Nat Methods |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5473255/ https://ncbi.nlm.nih.gov/pubmed/28418000 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.4263 |
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