p53‐independent Noxa induction by cisplatin is regulated by ATF3/ATF4 in head and neck squamous cell carcinoma cells

The platinum‐based DNA damaging agent cisplatin is used as a standard therapy for locally advanced head and neck squamous cell carcinoma (HNSCC). However, the mechanisms underpinning the cytotoxic effects of this compound are not entirely elucidated. Cisplatin produces anticancer effects primarily v...

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Bibliographische Detailangaben
Veröffentlicht in:Mol Oncol
Hauptverfasser: Sharma, Kanika, Vu, Thien‐Trang, Cook, Wade, Naseri, Mitra, Zhan, Kevin, Nakajima, Wataru, Harada, Hisashi
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2018
Schlagworte:
Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5983129/
https://ncbi.nlm.nih.gov/pubmed/29352505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12172
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