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p53‐independent Noxa induction by cisplatin is regulated by ATF3/ATF4 in head and neck squamous cell carcinoma cells

The platinum‐based DNA damaging agent cisplatin is used as a standard therapy for locally advanced head and neck squamous cell carcinoma (HNSCC). However, the mechanisms underpinning the cytotoxic effects of this compound are not entirely elucidated. Cisplatin produces anticancer effects primarily v...

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Detalhes bibliográficos
Publicado no:Mol Oncol
Main Authors: Sharma, Kanika, Vu, Thien‐Trang, Cook, Wade, Naseri, Mitra, Zhan, Kevin, Nakajima, Wataru, Harada, Hisashi
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5983129/
https://ncbi.nlm.nih.gov/pubmed/29352505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/1878-0261.12172
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