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Combination of fenretinide and ABT-263 induces apoptosis through NOXA for head and neck squamous cell carcinoma treatment

The overall survival for recurrent or metastatic head and neck squamous cell carcinoma (HNSCC) remains low, with little progress made over decades. Cisplatin, most frequently used for HNSCC treatment, activates mitochondria-dependent apoptosis through the BCL-2 family proteins. We have previously de...

詳細記述

保存先:
書誌詳細
出版年:PLoS One
主要な著者: Britt, Erin L., Raman, Sarina, Leek, Kendall, Sheehy, Casey H., Kim, Sung W., Harada, Hisashi
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2019
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6611623/
https://ncbi.nlm.nih.gov/pubmed/31276572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0219398
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