Combination with vorinostat overcomes ABT-263 (navitoclax) resistance of small cell lung cancer

Small cell lung cancer (SCLC) is an aggressive tumor type with high mortality. One promising approach for SCLC treatment would be to utilize agents targeting molecular abnormalities regulating resistance to apoptosis. BH3 mimetic antagonists, such as ABT-737 and its orally available derivative ABT-2...

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Detalhes bibliográficos
Publicado no:Cancer Biol Ther
Main Authors: Nakajima, Wataru, Sharma, Kanika, Hicks, Mark A., Le, Ngoc, Brown, Rikiara, Krystal, Geoffrey W., Harada, Hisashi
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4847809/
https://ncbi.nlm.nih.gov/pubmed/26575826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2015.1108485
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