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Combination with vorinostat overcomes ABT-263 (navitoclax) resistance of small cell lung cancer

Small cell lung cancer (SCLC) is an aggressive tumor type with high mortality. One promising approach for SCLC treatment would be to utilize agents targeting molecular abnormalities regulating resistance to apoptosis. BH3 mimetic antagonists, such as ABT-737 and its orally available derivative ABT-2...

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Podrobná bibliografie
Vydáno v:Cancer Biol Ther
Hlavní autoři: Nakajima, Wataru, Sharma, Kanika, Hicks, Mark A., Le, Ngoc, Brown, Rikiara, Krystal, Geoffrey W., Harada, Hisashi
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4847809/
https://ncbi.nlm.nih.gov/pubmed/26575826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2015.1108485
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