Andrographolide Induces Noxa-Dependent Apoptosis by Transactivating ATF4 in Human Lung Adenocarcinoma Cells

Lung adenocarcinoma is the most common pathological type of lung cancer with poor patient outcomes; therefore, developing novel therapeutic agents is critically needed. Andrographolide (AD), a major active component derived from the traditional Chinese medicine (TCM) Andrographis paniculate, is a po...

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Publicat a:Front Pharmacol
Autors principals: Zhang, Junqian, Li, Chunjie, Zhang, Li, Heng, Yongqing, Xu, Tong, Zhang, Yunjing, Chen, Xihui, Hoffman, Robert M, Jia, Lijun
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2021
Matèries:
Pharmacology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8117100/
https://ncbi.nlm.nih.gov/pubmed/33995110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.680589
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