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The mitochondrial protease HtrA2 restricts the NLRP3 and AIM2 inflammasomes
Activation of the inflammasome pathway is crucial for effective intracellular host defense. The mitochondrial network plays an important role in inflammasome regulation but the mechanisms linking mitochondrial homeostasis to attenuation of inflammasome activation are not fully understood. Here, we r...
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| Veröffentlicht in: | Sci Rep |
|---|---|
| Hauptverfasser: | , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5981608/ https://ncbi.nlm.nih.gov/pubmed/29855523 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-26603-1 |
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