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Structure, Activation and Regulation of NLRP3 and AIM2 Inflammasomes
The inflammasome is a three-component (sensor, adaptor, and effector) filamentous signaling platform that shields from multiple pathogenic infections by stimulating the proteolytical maturation of proinflammatory cytokines and pyroptotic cell death. The signaling process initiates with the detection...
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| Pubblicato in: | Int J Mol Sci |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
MDPI
2021
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7830601/ https://ncbi.nlm.nih.gov/pubmed/33467177 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22020872 |
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