Ligand Screening Systems for Human Glucose Transporters as Tools in Drug Discovery

Hexoses are the major source of energy and carbon skeletons for biosynthetic processes in all kingdoms of life. Their cellular uptake is mediated by specialized transporters, including glucose transporters (GLUT, SLC2 gene family). Malfunction or altered expression pattern of GLUTs in humans is asso...

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Vydáno v:Front Chem
Hlavní autoři: Schmidl, Sina, Iancu, Cristina V., Choe, Jun-yong, Oreb, Mislav
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2018
Témata:
Chemistry
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5980966/
https://ncbi.nlm.nih.gov/pubmed/29888221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2018.00183
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