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Ligand Screening Systems for Human Glucose Transporters as Tools in Drug Discovery

Hexoses are the major source of energy and carbon skeletons for biosynthetic processes in all kingdoms of life. Their cellular uptake is mediated by specialized transporters, including glucose transporters (GLUT, SLC2 gene family). Malfunction or altered expression pattern of GLUTs in humans is asso...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Front Chem
Main Authors: Schmidl, Sina, Iancu, Cristina V., Choe, Jun-yong, Oreb, Mislav
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5980966/
https://ncbi.nlm.nih.gov/pubmed/29888221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2018.00183
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