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Allosteric Activation of GDP-Bound Ras Isoforms by Bisphenol Derivative Plasticisers
The protein family of small GTPases controls cellular processes by acting as a binary switch between an active and an inactive state. The most prominent family members are H-Ras, N-Ras, and K-Ras isoforms, which are highly related and frequently mutated in cancer. Bisphenols are widespread in modern...
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| Udgivet i: | Int J Mol Sci |
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| Main Authors: | , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
MDPI
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5979466/ https://ncbi.nlm.nih.gov/pubmed/29642594 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19041133 |
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