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The structural basis for the transition from Ras-GTP to Ras-GDP
The conformational changes in Ras that accompany the hydrolysis of GTP are critical to its function as a molecular switch in signaling pathways. Understanding how GTP is hydrolyzed by revealing the sequence of intermediary structures in the reaction is essential for understanding Ras signaling. Unti...
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| Main Authors: | , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2002
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC129411/ https://ncbi.nlm.nih.gov/pubmed/12213964 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.192453199 |
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