The binding affinity of PTPN13’s tandem PDZ2/3 domain is allosterically modulated

BACKGROUND: Protein tyrosine phosphatase PTPN13, also known as PTP-BL in mice, is a large multi-domain non-transmembrane scaffolding protein with a molecular mass of 270 kDa. It is involved in the regulation of several cellular processes such as cytokinesis and actin-cytoskeletal rearrangement. The...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:BMC Mol Cell Biol
Main Authors: Dicks, Markus, Kock, Gerd, Kohl, Bastian, Zhong, Xueyin, Pütz, Stefanie, Heumann, Rolf, Erdmann, Kai S., Stoll, Raphael
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6615252/
https://ncbi.nlm.nih.gov/pubmed/31286859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12860-019-0203-6
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados