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The binding affinity of PTPN13’s tandem PDZ2/3 domain is allosterically modulated
BACKGROUND: Protein tyrosine phosphatase PTPN13, also known as PTP-BL in mice, is a large multi-domain non-transmembrane scaffolding protein with a molecular mass of 270 kDa. It is involved in the regulation of several cellular processes such as cytokinesis and actin-cytoskeletal rearrangement. The...
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| Publicado en: | BMC Mol Cell Biol |
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| Autores principales: | , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
BioMed Central
2019
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6615252/ https://ncbi.nlm.nih.gov/pubmed/31286859 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12860-019-0203-6 |
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