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CD147 Promotes CXCL1 Expression and Modulates Liver Fibrogenesis

Activated hepatic stellate cells (HSCs) release pro-inflammatory and pro-fibrogenic factors. CXC chemokine-ligand-1 (CXCL1) is expressed on HSCs. We previously found that the CD147 is overexpressed in activated HSCs. In this study, we showed an important role of CD147 in promoting liver fibrosis by...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Shi, Wen-Pu, Ju, Di, Li, Hao, Yuan, Lin, Cui, Jian, Luo, Dan, Chen, Zhi-Nan, Bian, Huijie
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5979418/
https://ncbi.nlm.nih.gov/pubmed/29642635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19041145
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