Hepatocyte Produced Matrix Metalloproteinases Are Regulated by CD147 in Liver Fibrogenesis

BACKGROUND: The classical paradigm of liver injury asserts that hepatic stellate cells (HSC) produce, remodel and turnover the abnormal extracellular matrix (ECM) of fibrosis via matrix metalloproteinases (MMPs). In extrahepatic tissues MMP production is regulated by a number of mechanisms including...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Calabro, Sarah R., Maczurek, Annette E., Morgan, Alison J., Tu, Thomas, Wen, Victoria W., Yee, Christine, Mridha, Auvro, Lee, Maggie, d'Avigdor, William, Locarnini, Stephen A., McCaughan, Geoffrey W., Warner, Fiona J., McLennan, Susan V., Shackel, Nicholas A.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Public Library of Science 2014
Θέματα:
Research Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4116334/
https://ncbi.nlm.nih.gov/pubmed/25076423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0090571
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