CD147 mediates intrahepatic leukocyte aggregation and determines the extent of liver injury

BACKGROUND: Chronic inflammation is the driver of liver injury and results in progressive fibrosis and eventual cirrhosis with consequences including both liver failure and liver cancer. We have previously described increased expression of the highly multifunctional glycoprotein CD147 in liver injur...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Yee, Christine, Main, Nathan M., Terry, Alexandra, Stevanovski, Igor, Maczurek, Annette, Morgan, Alison J., Calabro, Sarah, Potter, Alison J., Iemma, Tina L., Bowen, David G., Ahlenstiel, Golo, Warner, Fiona J., McCaughan, Geoffrey W., McLennan, Susan V., Shackel, Nicholas A.
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2019
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6619953/
https://ncbi.nlm.nih.gov/pubmed/31291257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0215557
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