CD147 mediates intrahepatic leukocyte aggregation and determines the extent of liver injury

BACKGROUND: Chronic inflammation is the driver of liver injury and results in progressive fibrosis and eventual cirrhosis with consequences including both liver failure and liver cancer. We have previously described increased expression of the highly multifunctional glycoprotein CD147 in liver injur...

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Vydáno v:PLoS One
Hlavní autoři: Yee, Christine, Main, Nathan M., Terry, Alexandra, Stevanovski, Igor, Maczurek, Annette, Morgan, Alison J., Calabro, Sarah, Potter, Alison J., Iemma, Tina L., Bowen, David G., Ahlenstiel, Golo, Warner, Fiona J., McCaughan, Geoffrey W., McLennan, Susan V., Shackel, Nicholas A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2019
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6619953/
https://ncbi.nlm.nih.gov/pubmed/31291257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0215557
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