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CD147 mediates intrahepatic leukocyte aggregation and determines the extent of liver injury

BACKGROUND: Chronic inflammation is the driver of liver injury and results in progressive fibrosis and eventual cirrhosis with consequences including both liver failure and liver cancer. We have previously described increased expression of the highly multifunctional glycoprotein CD147 in liver injur...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Yee, Christine, Main, Nathan M., Terry, Alexandra, Stevanovski, Igor, Maczurek, Annette, Morgan, Alison J., Calabro, Sarah, Potter, Alison J., Iemma, Tina L., Bowen, David G., Ahlenstiel, Golo, Warner, Fiona J., McCaughan, Geoffrey W., McLennan, Susan V., Shackel, Nicholas A.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6619953/
https://ncbi.nlm.nih.gov/pubmed/31291257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0215557
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