Accumulation of Deleterious Passenger Mutations Is Associated with the Progression of Hepatocellular Carcinoma

In hepatocellular carcinoma (HCC), somatic genome-wide DNA mutations are numerous, universal and heterogeneous. Some of these somatic mutations are drivers of the malignant process but the vast majority are passenger mutations. These passenger mutations can be deleterious to individual protein funct...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS One
Prif Awduron: Budzinska, Magdalena A., Tu, Thomas, d’Avigdor, William M. H., McCaughan, Geoffrey W., Luciani, Fabio, Shackel, Nicholas A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2016
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5025244/
https://ncbi.nlm.nih.gov/pubmed/27631787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0162586
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