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Impact of deleterious passenger mutations on cancer progression
Cancer progression is driven by the accumulation of a small number of genetic alterations. However, these few driver alterations reside in a cancer genome alongside tens of thousands of additional mutations termed passengers. Passengers are widely believed to have no role in cancer, yet many passeng...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3581883/ https://ncbi.nlm.nih.gov/pubmed/23388632 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1213968110 |
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