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CD147 Promotes CXCL1 Expression and Modulates Liver Fibrogenesis

Activated hepatic stellate cells (HSCs) release pro-inflammatory and pro-fibrogenic factors. CXC chemokine-ligand-1 (CXCL1) is expressed on HSCs. We previously found that the CD147 is overexpressed in activated HSCs. In this study, we showed an important role of CD147 in promoting liver fibrosis by...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Shi, Wen-Pu, Ju, Di, Li, Hao, Yuan, Lin, Cui, Jian, Luo, Dan, Chen, Zhi-Nan, Bian, Huijie
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5979418/
https://ncbi.nlm.nih.gov/pubmed/29642635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19041145
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