Basolateral CD147 induces hepatocyte polarity loss by E‐cadherin ubiquitination and degradation in hepatocellular carcinoma progress

Hepatocytes are epithelial cells with highly specialized polarity. The disorder and loss of hepatocyte polarity leads to a weakness of cell adhesion and connection, the induction of epithelial–mesenchymal transition, and eventually the occurrence of hepatocellular carcinoma (HCC). Cluster of differe...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Hepatology
Main Authors: Lu, Meng, Wu, Jiao, Hao, Zhi‐Wei, Shang, Yu‐Kui, Xu, Jing, Nan, Gang, Li, Xia, Chen, Zhi‐Nan, Bian, Huijie
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2018
Teme:
Original Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6055794/
https://ncbi.nlm.nih.gov/pubmed/29356040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.29798
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