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Basolateral CD147 induces hepatocyte polarity loss by E‐cadherin ubiquitination and degradation in hepatocellular carcinoma progress

Hepatocytes are epithelial cells with highly specialized polarity. The disorder and loss of hepatocyte polarity leads to a weakness of cell adhesion and connection, the induction of epithelial–mesenchymal transition, and eventually the occurrence of hepatocellular carcinoma (HCC). Cluster of differe...

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Detalles Bibliográficos
Publicado en:Hepatology
Main Authors: Lu, Meng, Wu, Jiao, Hao, Zhi‐Wei, Shang, Yu‐Kui, Xu, Jing, Nan, Gang, Li, Xia, Chen, Zhi‐Nan, Bian, Huijie
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6055794/
https://ncbi.nlm.nih.gov/pubmed/29356040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.29798
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