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Basolateral CD147 induces hepatocyte polarity loss by E‐cadherin ubiquitination and degradation in hepatocellular carcinoma progress

Hepatocytes are epithelial cells with highly specialized polarity. The disorder and loss of hepatocyte polarity leads to a weakness of cell adhesion and connection, the induction of epithelial–mesenchymal transition, and eventually the occurrence of hepatocellular carcinoma (HCC). Cluster of differe...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Hepatology
Hauptverfasser: Lu, Meng, Wu, Jiao, Hao, Zhi‐Wei, Shang, Yu‐Kui, Xu, Jing, Nan, Gang, Li, Xia, Chen, Zhi‐Nan, Bian, Huijie
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6055794/
https://ncbi.nlm.nih.gov/pubmed/29356040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.29798
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