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Full-length soluble CD147 promotes MMP-2 expression and is a potential serological marker in detection of hepatocellular carcinoma

BACKGROUND: As a surface glycoprotein, CD147 is capable of stimulating the production of matrix metalloproteinases (MMPs) from neighboring fibroblasts. The aim of the present study is to explore the role of soluble CD147 on MMPs secretion from hepatocellular carcinoma (HCC) cells, and to investigate...

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Détails bibliographiques
Publié dans:J Transl Med
Auteurs principaux: Wu, Jiao, Hao, Zhi-Wei, Zhao, You-Xu, Yang, Xiang-Min, Tang, Hao, Zhang, Xin, Song, Fei, Sun, Xiu-Xuan, Wang, Bin, Nan, Gang, Chen, Zhi-Nan, Bian, Huijie
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2014
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4227008/
https://ncbi.nlm.nih.gov/pubmed/24996644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-12-190
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