Doxycycline Inducible Chimeric Antigen Receptor T Cells Targeting CD147 for Hepatocellular Carcinoma Therapy

Chimeric antigen receptor T cell (CAR-T) therapy to hematological malignancies has demonstrated tremendous clinical outcomes. However, the therapeutic efficacy of CAR-T cells in solid tumors remains limited due to the scarcity of tumor-specific antigen targets and the poor infiltration of CAR-T cell...

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Udgivet i:Front Cell Dev Biol
Main Authors: Zhang, Ren-Yu, Wei, Ding, Liu, Ze-Kun, Yong, Yu-Le, Wei, Wei, Zhang, Zhi-Yun, Lv, Jian-Jun, Zhang, Zhao, Chen, Zhi-Nan, Bian, Huijie
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
Fag:
Cell and Developmental Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6798074/
https://ncbi.nlm.nih.gov/pubmed/31681766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2019.00233
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