HIV-1 Nef impairs MHC class II antigen presentation and surface expression
HIV-1-infected cells can avoid cytotoxic T lymphocyte killing by Nef-mediated down-regulation of surface MHC I. Here, we show that HIV-1 Nef inhibits MHC II restricted peptide presentation to specific T cells and thus may affect the induction of antiviral immune responses. Nef mediates this effect b...
Zapisane w:
| Wydane w: | Proc Natl Acad Sci U S A |
|---|---|
| Główni autorzy: | , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
National Academy of Sciences
2001
|
| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC59782/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11593029/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.221256498 |
| Etykiety: |
Nie ma etykietki, Dołącz pierwszą etykiete!
|
