HIV-1 Nef impairs MHC class II antigen presentation and surface expression

HIV-1-infected cells can avoid cytotoxic T lymphocyte killing by Nef-mediated down-regulation of surface MHC I. Here, we show that HIV-1 Nef inhibits MHC II restricted peptide presentation to specific T cells and thus may affect the induction of antiviral immune responses. Nef mediates this effect b...

Description complète

Enregistré dans:
Détails bibliographiques
Auteurs principaux: Stumptner-Cuvelette, Pamela, Morchoisne, Stephanie, Dugast, Marc, Le Gall, Sylvie, Raposo, Graça, Schwartz, Olivier, Benaroch, Philippe
Format: Artigo
Langue:Inglês
Publié: The National Academy of Sciences 2001
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC59782/
https://ncbi.nlm.nih.gov/pubmed/11593029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.221256498
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires