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Cationic Liposomes Carrying siRNA: Impact of Lipid Composition on Physicochemical Properties, Cytotoxicity and Endosomal Escape

In recent year, cationic liposomes have gained a lot of attention for siRNA delivery. Despite this, intracellular barriers as endosomal escape and cytosolic delivery of siRNA still represent a challeng, as well as the cytotoxicity due to cationic lipids. To address these issues, we developed four li...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Nanomaterials (Basel)
Main Authors: Lechanteur, Anna, Sanna, Vincent, Duchemin, Amandine, Evrard, Brigitte, Mottet, Denis, Piel, Géraldine
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5977284/
https://ncbi.nlm.nih.gov/pubmed/29695068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/nano8050270
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