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Multifunctional Cationic Lipid-Based Nanoparticles Facilitate Endosomal Escape and Reduction-Triggered Cytosolic siRNA Release

Small interfering RNA (siRNA) has garnered much attention in recent years as a promising avenue for cancer gene therapy due to its ability to silence disease-related genes. Effective gene silencing is contingent upon the delivery of siRNA into the cytosol of target cells and requires the implementat...

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Bibliografski detalji
Izdano u:Mol Pharm
Glavni autori: Gujrati, Maneesh, Malamas, Anthony, Shin, Tesia, Jin, Erlei, Sun, Lulu, Lu, Zheng-Rong
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4457381/
https://ncbi.nlm.nih.gov/pubmed/25020033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp400787s
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